LONDON - Gareth Southgate's side host Germany at Wembley at 1600 GMT in what is England's biggest match on home turf for 25 years.
England beat the Germans to win the 1966 World Cup final, but their major tournament history has been littered with painful exits against them since then.
A quarter-final loss at the 1970 World Cup ended England's reign as champions, while the 1990 World Cup semi-final defeat on penalties is still etched in the nation's psyche.
When England last played at home in a tournament, Southgate was the Euro 96 fall guy as he missed a crucial penalty in the semi-final shoot-out defeat.
There was also a heavy defeat at the 2010 World Cup yet Southgate, aware of the debilitating weight of that history, insists the tie is not a chance to exorcise the ghosts of past England failures.
Instead, he believe it is a chance for his players to add a memorable new chapter to their personal stories.
"This team, I've said for a long time, have had so many unique achievements and my focus is on this team and helping them to succeed," Southgate said.
"This is about our players. This is their moment and it's their opportunity."
- 'Loser goes home' -
Asked if perhaps his Euro 96 pain would give his players extra motivation to win it for him, Southgate said: "Good grief, no. I don't think we'll be relying on that!
"So, no, this is about them. This is about them having a chance to achieve something, and certainly not for me to take any shine off of that."
England have never won the European Championship and a victory against Germany would be only their second knockout stage win in the history of the competition.
In contrast, Germany have been crowned kings of Europe three times, with the most recent success coming in 1996.
However, Germany travelled to London in the unusual position of fearing defeat against England.
Joachim Loew's team stumbled into the last 16 after rescuing a 2-2 draw against Hungary in their final group game.
Germany are not the intimidating force of old and, with Loew stepping down at the end of the tournament, a defeat would signal the end of an era.
Despite winning the World Cup in 2014, Loew has been criticised for his role in a humiliating group-stage exit from the 2018 World Cup and a series of poor results before the Euro.
"All in all, I thought about it for two seconds," said Loew ahead of potentially his last game.
"This is my passion. My whole focus is on the match and I hope we will succeed."
England will have the vast majority of a 40,000 crowd on their side at Wembley and Loew expects a spine-tingling encounter.
"This is a match which electrifies everybody. For both teams, it's in or out, it's now or never, the loser goes home," he said.
The winner will face a quarter-final in Rome against the winner of Tuesday's late tie between Sweden and Ukraine, which will be played in Glasgow.
- Mbappe misses decisive penalty -
Whatever happens on Tuesday it will struggle to live up to the drama of Monday, when world champions France suffered a stunning defeat against Switzerland, losing 5-4 on penalties after a thrilling 3-3 draw in Bucharest as Kylian Mbappe missed the vital kick.
France trailed to Haris Seferovic's first-half header and could have fallen further behind when Ricardo Rodriguez's 55th-minute penalty was saved by Hugo Lloris.
Karim Benzema scored twice in 244 seconds immediately after that miss to put France ahead.
Paul Pogba increased their lead with a stunning strike, but Seferovic struck again in the 81st minute and Mario Gavranovic equalised in stoppage time.
Yann Sommer was Switzerland's hero in the shootout as the goalkeeper saved Mbappe's penalty to seal an incredible giant-killing.
"Penalties are always cruel for one team and unfortunately it was us," said France coach Didier Deschamps.
"We are not used to it, but we will have to accept it."
In the quarter-finals, Switzerland face Spain, who hit back for an epic 5-3 extra-time win against Croatia after blowing the lead in Copenhagen.
Pablo Sarabia, Cesar Azpilicueta and Ferran Torres netted to put Spain 3-1 ahead with 13 minutes left after Pedri's own goal had given Croatia the lead.
Mislav Orsic and Mario Pasalic scored in the last five minutes to force extra time, but Spain prevailed thanks to goals from Alvaro Morata and Mikel Oyarzabal. - AFP, 29 June, 2021
