World

Baby with DNA from three people born in the UK

Specialised IVF procedure offers hope for preventing inheritance of defective genes

Updated 3 years ago · Published on 10 May 2023 1:00PM

Baby with DNA from three people born in the UK
According to reports, the Human Fertilisation and Embryology Authority confirmed ‘less than five’ babies have been born in the UK after mitochondrial donation treatment as of April 20 this year. – Pixabay pic, May 10, 2023

LONDON – The first baby with DNA from three people has been born in the United Kingdom, after a special IVF procedure, the fertility regulator said, reported German news agency dpa.

According to reports, the Human Fertilisation and Embryology Authority (HFEA) confirmed “less than five” babies have been born in the UK after mitochondrial donation treatment as of April 20 this year.

HFEA did not give further details to avoid families being identified, The Guardian reported after receiving the information from a freedom of information request.

The aim of the treatment is to avoid women passing on defective genes in the mitochondria – tiny rod-like power plants in cells that supply energy – and prevent children from inheriting conditions.

The technique involves giving a woman an IVF baby with DNA from three individuals.

The baby will have nuclear DNA from its mother and father, defining key characteristics, such as personality and eye colour.

In addition, it will have a tiny amount of mitochondrial DNA provided by a female donor – the third “parent”.

Britain became the first country in the world to formally allow mitochondrial replacement therapy (MRT) when the HFEA gave a cautious green light to the procedure in 2017.

In 2018, fertility doctors at the Newcastle Fertility Centre at Life were given permission by the HFEA to give two women MRT.

In 2015, MPs and peers paved the way for the change by voting to alter the Human Fertilisation and Embryology Act, which sets the legal framework for fertility research and treatment. – Bernama, May 10, 2023

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